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The Price of DNA Sequencing Dropped From $2.7 Billion to $300 in Less Than 20 Years

Nebula Genomics is offering access to your entire genetic makeup for less than the price of an Apple Watch

Emily Mullin
OneZero
4 min readFeb 18, 2020

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A sequencing chromatograph showing a DNA sequence and a sample of DNA from the human genome mapping project.
Photo: Science & Society Picture Library/SSPL/Getty Images

GGenome sequencing was once impossibly expensive. The Human Genome Project, an international effort to decode the human genome that launched in 1990, took 13 years and an estimated $2.7 billion to complete. Then, in 2007, DNA pioneer James Watson became the first person to get his genome sequenced for less than $1 million. Since then, the cost of genome sequencing has been decreasing at a rate faster than Moore’s law.

Now, Nebula Genomics, a spinout of Harvard University co-founded by geneticist George Church, is launching an at-home whole genome sequencing test for less than the price of the latest Apple Watch. At $299, Nebula’s service provides a readout of a person’s entire genetic code.

Nebula’s sequencing is a much more comprehensive test than the ones offered by companies like 23andMe and Ancestry, which use a different technique called genotyping. Genotyping looks at only a small part of the genome. For instance, 23andMe’s $199 health and ancestry test reports on a handful of genetic variants associated with about a dozen health conditions. Sequencing looks at all of a…

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OneZero
OneZero

Published in OneZero

OneZero is a former publication from Medium about the impact of technology on people and the future. Currently inactive and not taking submissions.

Emily Mullin
Emily Mullin

Written by Emily Mullin

Former staff writer at Medium, where I covered biotech, genetics, and Covid-19 for OneZero, Future Human, Elemental, and the Coronavirus Blog.

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