The Government Plan to Build Radiation-Proof CRISPR Soldiers

A DARPA project aims to temporarily alter human genes, and shield people from deadly radiation exposure

Emily Mullin
OneZero

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Illustration: Eva Redamonti

InIn the early morning hours of April 26, 1986, the Chernobyl Nuclear Power Plant in Ukraine exploded, releasing a cloud of toxic fumes and radioactive particles. The fire burned for 10 days, as hundreds of plant staff, firefighters, and emergency responders desperately worked, often without proper safety equipment, to quench the blaze.

Of those, 134 people were eventually diagnosed with acute radiation syndrome, the illness that occurs when a person is exposed to a high dose of radiation across the entire body in a short period of time. Though Chernobyl’s total death toll is still disputed, it has been conclusively documented that 28 first responders died in the three months after the accident from radiation exposure.

In the decades since the Chernobyl disaster, treatment for acute radiation syndrome has remained much the same — supportive care designed to help the body withstand the toxicity of radiation — despite billions of dollars of public investment into medical countermeasures. But an ambitious U.S. government project could change that. The Defense Advanced Research Projects Agency (DARPA), which develops…

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Emily Mullin
OneZero

Former staff writer at Medium, where I covered biotech, genetics, and Covid-19 for OneZero, Future Human, Elemental, and the Coronavirus Blog.