Surgeons Are Transplanting Genetically Engineered Pig Skin Onto Humans

It’s a key first step toward using pigs to solve the world’s donor organ shortage

Emily Mullin
OneZero

--

Credit: Minipigs/Wikimedia Commons

InIn a pathogen-free facility in Grafton, Massachusetts, a small town about 40 miles west of Boston, genetically engineered miniature pigs are being bred to donate their skin to humans.

Their skin, which looks remarkably similar to the human variety and is referred to as Xeno-Skin, will be transplanted by surgeons at Massachusetts General Hospital to a small group of burn victims in an attempt to speed up the healing process. It’s the first experiment approved by the U.S. Food and Drug Administration to use genetically engineered animal tissue in humans, a necessary step toward someday transferring entire organs grown in animals to people who need them — a process known as xenotransplantation.

The need for such organs is dire. Each day, 20 people die waiting for an organ transplant. More than 113,000 people in the United States are currently waiting for one, while only 36,528 transplants were performed in 2018, according to government data. Every year, the waiting list grows, greatly outpacing the number of available organs. For decades, researchers looked to animal donors as a way to ease this chronic shortage, but transplants from animals…

--

--

Emily Mullin
OneZero

Former staff writer at Medium, where I covered biotech, genetics, and Covid-19 for OneZero, Future Human, Elemental, and the Coronavirus Blog.