In U.S. First, Scientists Safely Edit Cancer Patients’ Cells With CRISPR

The pioneering study is backed by tech billionaire Sean Parker

Emily Mullin
OneZero

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A microscope image of a T cell. Credit: National Institute of Allergy and Infectious Diseases

OnOn Wednesday, U.S. scientists announced that they used the gene-editing tool CRISPR to modify the cells of cancer patients — a first in the United States — and that so far, the technique appears to be safe. It’s too early to tell whether the edited cells will help patients live longer, but researchers think the approach looks promising and is an important first step for using CRISPR against other diseases.

There’s an incredible amount of optimism around using CRISPR to treat or possibly cure a wide range of genetic disorders and cancers by snipping out detrimental strands of DNA from cells. The technology has drawn the attention of high-profile investors, including billionaire Sean Parker, co-founder of Napster and an early investor in Facebook, who helped fund the study. The idea is that CRISPR could eliminate disease at its source, rather than just alleviating symptoms, as the vast majority of pharmaceuticals on the market do. But CRISPR is a relatively new tool, and it is unclear how safe it is for human treatment. While experiments in animal subjects have looked promising, this new research gives scientists the first glimpse of how CRISPR will perform in people.

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Emily Mullin
OneZero

Former staff writer at Medium, where I covered biotech, genetics, and Covid-19 for OneZero, Future Human, Elemental, and the Coronavirus Blog.