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How can monkey-human hybrid embryos help fix the organ shortage?

It’s all about the blastoids

Alex Pearlman
OneZero
5 min readMay 26, 2021

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We have an organ shortage.

People are desperate for organs, but there is no easy way to make more. It would be awesome if we could use a summoning charm (accio membrum?) to create and distribute kidneys and livers, but unless we radically change our approach — or create human organs that we can harvest from animals — we’re shit out of luck.

Last month, a new milestone in attempts to advance medical treatment of humans by using animals, in this case a monkey, kicked off a barrage of commentary from ethicists and scientists. (I link to a lot of that below.)

Weizhi Ji/Kunming University of Science and Technology

The scientists at the Salk Institute, led by the prolific regenerative medicine pioneer Juan Carlos Izpisua Belmonte, added human cells to monkey embryos and they grew for almost 3 weeks, until the last of them died at 19 days. According to Stat, “On average, 3% to 4% of the cells in the embryos were human, and in one embryo, up to 7% were.”

The future outcomes are uncertain, and critics will decry the creation of something that seems like it’s out of a Charlton Heston film.

But one thing seems to be true: Scientists will continue on this trajectory, and we might just find a way to save lives with hybrid organs.

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OneZero
OneZero

Published in OneZero

OneZero is a former publication from Medium about the impact of technology on people and the future. Currently inactive and not taking submissions.

Alex Pearlman
Alex Pearlman

Written by Alex Pearlman

Reporter. Bioethicist. Publishing on the intersection of ethics and policy with emerging science and tech.

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